Two sample MR report
ELP5_Alveolar Macrophages against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.0534940 | 0.1489097 | 0.7340898 |
| Weighted median | 7 | -0.0250546 | 0.0087819 | 0.0043310 |
| Inverse variance weighted | 7 | -0.0262988 | 0.0067870 | 0.0001067 |
| Simple mode | 7 | -0.0242371 | 0.0116929 | 0.0835620 |
| Weighted mode | 7 | -0.0239818 | 0.0114603 | 0.0813066 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1620248 | 5 | 0.9994694 |
| Inverse variance weighted | 0.4497541 | 6 | 0.9983973 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.05335 | 0.0994587 | 0.6146757 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000102 | 0 | TRUE | 0.338597 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
